Acute and subchronic toxicological evaluation of Echinophora platyloba DC (Apiaceae) total extract in Wistar rats

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Acute and subchronic toxicological evaluation of Echinophora platyloba DC (Apiaceae) total extract in Wistar rats

OBJECTIVE Echinophora platyloba DC is a widely used herbal medicine and food seasoning in Iran. It is claimed to exert antimicrobial, antifungal, and antispasmodic effects. Despite the prevalent use of this plant as a food and medicine, there are no reports on its possible toxic effects. To evaluate the safety of E. platyloba, we tested its acute and sub-chronic toxicity in male and female Wist...

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Acute and subchronic toxicological evaluation of Stachys lavandulifolia aqueous extract in Wistar rats

Stachys lavandulifolia (S. lavandulifolia) is a plant that has been widely used as an herbal medicine in Iran. Unfortunately, despite the prevalent medicinal uses of the plant, there are no reports on the possible toxic effects of S. lavandulifolia. In the present study the potential toxicity of S. lavandulifolia after acute and subchronic administration in rats was evaluated. Rats were orally ...

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acute and subchronic toxicological evaluation of stachys lavandulifolia aqueous extract in wistar rats

stachys lavandulifolia ( s. lavandulifolia ) is a plant that has been widely used as an herbal medicine in iran. unfortunately, despite the prevalent medicinal uses of the plant, there are no reports on the possible toxic effects of s. lavandulifolia . in the present study the potential toxicity of s. lavandulifolia after acute and sub-chronic administration in rats was evaluated. rats were ora...

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Subchronic Toxicological Evaluation of Eupatorium Aschenbornianum in Wistar Rats

Eupatorium aschenbornianum is a plant used for the treatment of gastric ulcer, therefore, the present study aimed to evaluate the safety of this dehydrated plant in order to find the appropriate doses for further human studies. Male Wistar rats were fed with different incremental doses dehydrated plant from 200 to 1000 mg/kg bw in a subchronic test during 45 days. Animals were sacrificed, then ...

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Acute and subchronic toxicity assessment of Melastomastrum capitatum Fern. leaf methanol extract in Wistar albino rats

This study was carried in order to determine short-term (acute) and long-term(subchronic) effects of Melastomastrum capitatum leaf methanol extract in the management and treatment of certain diseases in traditional and complementary medicines  by many villages in Mambila Nigeria. Acute and subchronic toxicities were carried out in  accordance with the Organization for Economic Cooperation and D...

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ژورنال

عنوان ژورنال: Clinics

سال: 2012

ISSN: 1807-5932

DOI: 10.6061/clinics/2012(05)15